#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss

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Episode eighty six. In today's AMA, we're gonna look at the effects of GLP one receptor Agonists. So these are drugs like Ozempic, Bagovy, and Zet bound. But specifically, we're gonna look at the impact they have on muscle. We're gonna talk about how much lean mass people actually lose on these drugs and how that compares to weight loss by any other means. We're gonna define exactly what lean mass is and how loss of lean mass on DEXA

can actually mislead us. How these drugs impact bone mass and fracture risk. the all important effects of these drugs on strength and physical function, which probably should be the most important metric. The effect of these drugs on different fat depots across the body. Who's at most risk. for lean mass loss.

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