Modern Wisdom · 2026-05-25 · 162 min · 35,827 words

Mostly Wise: Matt McCusker, Andrew Huberman & Tom Segura - #1102

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I keep seeing tweets about how everyone should be taking erectile dysfunction medication. Is that true? Low grade, whatever, yeah, like lowphil. So tidalophil, which is the uh generic name for Cialis, was developed first as a prostate health drug. And then people took more of it and realized that at higher dosages it can be uh effective for erectile dysfunction.

But low dose is good for prostate health. Low dose, like 2.5 to 5 milligrams per day. is very helpful for perfusion of the prostate and also it causes vasodilation in the brain. So things like strokes. I mean you want blood flow, right?

You don't want excessive blood flow, but you're you've got a headache from it. But our uh chair of male sexual health and urology at Stanford, Mike Eisenberg, he came on the podcast and he said pretty much every male over 40 or so should be taking about 2.5 to 5 milligrams per day. Does it still get you pretty hard too? It definitely will improve just curious.

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