The Dr. Hyman Show · 2026-04-15 · 81 min · 17,612 words

Tired But Wired? The Hidden Loop Destroying Your Energy | Dr. Scott Sherr, MD

Listen to the original audio · Transcribed with NVIDIA Parakeet · Timestamps stay in sync with the live audio

I eat perfectly. I exercise six times a week. I try to get to bed on time and sleep. I'm feeling depleted. And I think people are in this state and they don't have a name for it, but you call it the sympathetic spiral of doom.

And it's a loop. You have sympathetic activation, which is your fight or flight, your nervous system being active. You have mitochondral dysfunction. The challenge is anytime you try to downregulate your nervous system, it actually might make you feel like you're crashing. People feel like they crash when they go down and try to do their breathwork, try to do their meditation.

Oftentimes they feel terrible when they try to do it, if they can even do it in the first place. You've only been able to function because you've been at that high of a step. You can't meditate your way out of this like physiological stress to your cells and mitochondria is what you're saying, right? So what do we do? If someone's stuck, what's the first step to getting out of this loop?

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