#388 — Prostate cancer screening: why current PSA guidelines are failing men and how modern tools improve early detection and save lives

Hey everyone, welcome to the Drive Podcast. I'm your host, Peter Atia. This podcast, my website, and my weekly newsletter all focus on the goal of translating the science of longevity into something accessible for everyone. Our goal is to provide the best content in health and wellness, and we've established a great team of analysts to make this happen. It is extremely important to me to provide all of this content without relying on paid ads.

To do this, our work is made entirely possible by our members, and in return, we offer exclusive member-only content and benefits above and beyond what is available for free. If you want to take your knowledge of this space to the next level, it's our goal to ensure members get back much more than the price of the subscription. If you want to learn more about the benefits of our premium membership, head over to peterateiamd.com forward slash subscribe. Welcome to a special episode of The Drive. In this episode, I'm going to walk through a single topic in depth, and this is prostate cancer screening.

Something that I'm very passionate about. And because we consider this a really important PSA, no pun intended, the full episode and the detailed show notes for this discussion will be available to everyone, regardless of whether or not you're a premium subscriber. In this episode, I discuss why advanced and metastatic prostate cancer diagnoses are rising despite the availability of screening tools. what PSA actually measures and why it's more useful when interpreted over time than it is in a single one-off number, how MRI, PSA density, PSA velocity, and improved biopsy techniques can reduce unnecessary procedures while improving the detection of aggressive cancers, how active surveillance helps avoid overtreatment in men with low risk cancers, why the evidence used to argue against PSA screening was deeply flawed, how drugs like phenasteride, which are commonly used to prevent hair loss, can suppress PSA and lead to missed warning signs if clinicians and patients are not vigilant, and why I think regular PSA testing is so important if one of our objectives in life would be to

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