#357 ‒ A new era of longevity science: models of aging, human trials of rapamycin, biological clocks, promising compounds, and lifestyle interventions | Brian Kennedy, Ph.D.

Hey everyone, welcome to the Drive Podcast. I'm your host, Peter Atia. This podcast, my website, and my weekly newsletter all focus on the goal of translating the science of longevity into something accessible for everyone. Our goal is to provide the best content in health and wellness, and we've established a great team of analysts to make this happen. It is extremely important to me to provide all of this content without relying on paid ads.

To do this, our work is made entirely possible by our members, and in return, we offer exclusive member-only content and benefits above and beyond what is available for free. If you want to take your knowledge of this space to the next level, it's our goal to ensure members get back much more than the price of the subscription. If you want to learn more about the benefits of our premium membership, head over to peterateiamd.com forward slash subscribe. My guest this week is Brian Kennedy. Brian is a renowned biologist and leader in the field of aging research.

He's the former CEO of the Buck Institute for Research. on aging, and he is now the director of the Center for Healthy Longevity at the National University of Singapore. In this episode, we discuss why Brian moved his research from the US to Singapore and how that shift opened the door to running larger scale clinical aging studies, how the field of longevity research changed around 2017 when serious funding started pouring in and reshaping priorities and the pace of discovery, We explore two different concepts of aging, one being the linear accumulation of wear and tear with age, but the other being the exponential or nonlinear increase in all-cause mortality with age. And again, I think Brian's explanation here is one of the more interesting ones I've heard.

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