#359 ‒ How metabolic and immune system dysfunction drive the aging process, the role of NAD, promising interventions, aging clocks, and more | Eric Verdin, M.D.

Hey everyone, welcome to the Drive Podcast. I'm your host, Peter Atia. This podcast, my website, and my weekly newsletter all focus on the goal of translating the science of longevity into something accessible for everyone. Our goal is to provide the best content in health and wellness. And we've established a great team of analysts to make this happen. It is extremely important to me to provide all of this content without relying on paid ads. To do this, our work is made entirely possible by our members, and in return, we offer exclusive member only content and benefits above and beyond what is available for free.

If you want to take your knowledge of this space to the next level, it's our goal to ensure members get back much more than the price of a subscription. If you want to learn more about the benefits of our premium membership, head over to peterateamd.com forward slash subscribe. My guest this week is Dr. Eric Verden. Eric is a physician scientist who spent two decades uncovering how epigenetics, metabolism, and the immune system. drive aging and now serves as the president and CEO of the Buck Institute for Research on Aging. In this episode we discuss Eric's path from studying viruses. and H DAX to leading the Buck Institute and focusing on aging research.

How aging changes the immune and nervous system. thymus shrinkage, for example, loss of T cell diversity, chronic inflammation. and weaker vaccine response and why these changes can ultimately shorten lifespan. Metabolic drivers of aging, oxidative stress, fuel choice, insulin, and IGF one signaling. And practical tips on zone two cardio.

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