The Peter Attia Drive · 2026-09-28 · 146 min · 24,064 words

#409 ‒ Inside modern drug development: the science, economics, and regulatory hurdles behind bringing new medicines to patients | Lloyd Klickstein, M.D., Ph.D.

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Hey everyone, welcome to the Drive Podcast. I'm your host, Peter Atia. This podcast, my website, and my weekly newsletter all focus on the goal of translating the science of longevity into something accessible for everyone. Our goal is to provide the best content in health and wellness, and we've established a great team of analysts to make this happen. It is extremely important to me to provide all of this content without relying on paid ads.

To do this, our work is made entirely possible by our members, and in return, we offer exclusive member-only content and benefits above and beyond what is available for free. If you want to take your knowledge of this space to the next level, it's our goal to ensure members get back much more than the price of the subscription. If you want to learn more about the benefits of our premium membership, head over to peterateiamd.com forward slash subscribe. My guest this week is Dr. Lloyd Clickstein, a physician, scientist, rheumatologist, and drug developer who has spent more than two decades helping discover and develop new medicines.

After beginning his career as a physician scientist at Harvard Medical School and the Brigham and Women's Hospital, Lloyd joined Novartis, where he helped pioneer translational medicine and led the company's new indication discovery unit, identifying entirely new disease and therapeutic opportunities. He later held leadership roles at several biotechnology companies, including Versantis Bio, where he led the development of BEMA before the company was acquired by Eli Lilly. Today he serves as the CEO of Coslap Therapeutics. I wanted to have Lloyd on because very few people have had a front row seat to every stage of modern drug development, from identifying the unmet medical need to the discovery of new therapeutic targets to navigating clinical trials, regulatory approval, and even commercialization.

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