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Intelligence Squared · 2026-02-18 · 42 min · 6,885 words

Will AI Design New Organisms From Scratch? With Adrian Woolfson

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Welcome to Intelligence Squared, where great minds meet. I'm producer Mia Sorrenti. Could AI allow us to edit DNA as easily as software? In this episode, Adrian Wolsen joins host Ganesh Taylor to discuss the opportunities at the intersection of synthetic biology and AI. Wolfson argues that AI is beginning to help us decode the grammar of the genome and could allow us to delete disease and even redesign organisms.

But who gets to choose? And what happens to ecosystems and human nature itself when genomes become editable? Let's join our host, Ganesh Taylor now with more. Welcome to Intelligence Squared. I'm Ganesh Taylor.

Our guest today is Adrian Wolfson. Adrian is the co-founder of Genero, a California-based biotechnology company specializing in synthetic genome design and construction. He studied medicine at Balliol College, Oxford, and was formerly the Charles and Catherine Darwin Research Fellow at Darwin College, Cambridge, working at the MRC Laboratory of Molecular Biology. He is the author of the critically acclaimed Life Without Genes, The History and Future of Genomes, and an intelligent person's guide to genetics. Today, I am delighted to be speaking to Adrian about his new book on the future of species, authoring life by means of artificial biological intelligence.

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