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The Dissenter · 2026-04-02 · 60 min · 10,067 words

#1235 Nicole Rust: Why Neuroscience Hasn’t Solved Brain Disorders―and How We Can Change That

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Hello everyone, welcome to a new episode of The Decenter. I'm your host as always, Ricardo Lopes, and today I'm joined by Dr. Nicole Rust. She's professor of psychology at the University of Pennsylvania, and today we're talking about her book, Illusive Cures, Why Neuroscience hasn't solved brain disorders and how we can change that. So Nicole, welcome to the show.

It's a pleasure to have you one. Oh, Ricardo, thank you so much for having me. It's a pleasure to be here. Okay, so first of all, what motivated you to write this book? So I've been a brain researcher for decades now, and I was hearing uh increasing calls about the disconnection.

between the sorts of things that brain researchers like myself had been discovering and the end goals that we need to achieve for society, which include, but are not limited to treatments and cures for brain and mental disorders of all types. And what really troubled me is I couldn't spell out how we're going to reach those end goals, right? Despite the fact that I have been a brain researcher for decades. And so for me, Part of elusive cures was really a personal journey to try to puzzle these things out, but I also reasoned that if I don't have a really clear picture of this through line in my own head, others probably don't as well.

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