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HBR IdeaCast · 2025-12-04 · 30 min · 4,956 words

Future of Business: Moderna’s Founder on Innovation That Breaks Through

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I'm Alison Beard and this is the HBR Ideacast. Today we're bringing you the third in our series of interviews with CEOs of major companies that we recorded during our recent future of business event. Nubara Fan is the founder and CEO of Flagship Pioneering. And co-founder and chair of Moderna, the mRNA vaccine company. He thinks deeply about how man and machine can work together to solve some of the world's largest problems, whether they're in the world of science, business, or society.

Now, we've spoken to him on Ideacast before back in 2021 to talk specifically about leadership and innovation lessons learned in the development of Moderna's COVID vaccine. scene. But things move fast in today's business world and his thinking has evolved accordingly. He's a trained biochemical engineer, entrepreneur, and executive who has helped spawn more than 100 life science and technology startups, so he has a unique vantage point as to what really works when it comes to effective innovation. I want to ask first, how do you define breakthrough innovation, not just in science, but across industries?

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