Huberman Lab · 2025-11-03 · 119 min · 24,703 words

Using Existing Drugs in New Ways to Treat & Cure Diseases of Brain & Body | Dr. David Fajgenbaum

Listen to the original audio · Transcribed with NVIDIA Parakeet · Timestamps stay in sync with the live audio

My doctor explained to me that we were out of options. He said, David, we've tried everything. You know, we tried these chemotherapies, we tried this one experimental drug. There's nothing more that we can do. There was a a few-minute period where my dad, my sisters, and and my girlfriend around me and we were just just bawling our eyes out.

You know, we're this is the world's expert. And I kept probing him, like, is there any cell type or signaling pathway? Is there something we can target? Like anything. He said, David, there's nothing.

Is there anything in an early stage development? David, there is nothing. I I heard what he was saying, but then I thought to myself, you just gave me seven chemotherapies that were made for lymphoma and my multima myeloma, and they've saved my life now three times. They're not, it's not long-term. Like I know I keep relapsing, but like if these seven chemotherapies are working, how do we know there's not an eighth chemotherapy or a ninth drug for something else?

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