podcast

The Peter Attia Drive

Peter Attia, MD

Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

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one credit per hour of audio for a new episode · 1 credit for one we have · up to 25 at a time

#406 ‒ Migraine, cluster headache, and tension headache: symptoms, causes, prevention, and treatment | Brian Grosberg, M.D. 2026-08-31 · 116m Open
#405 ‒ AMA #88: Metabolic liver health: how to assess risk, catch dysfunction early, and prevent or reverse liver disease 2026-08-24 · 39m Open
#404 ‒ Mental health beyond neurotransmitters: the role of hormones in psychiatry, why symptom reduction isn't enough, and the future of psychedelic therapies | Linus Abrams, M.D. 2026-08-17 · 138m Open
#403 ‒ Peptides: separating scientific promise from marketing hype 2026-08-10 · 53m Open
#402 ‒ NMR blood analysis: how heart disease risk, insulin resistance, inflammation, and mortality risk can be assessed from a single blood sample | Jim Otvos, Ph.D. 2026-08-03 · 145m Open
#401 ‒ How curiosity transforms medicine: extraordinary discoveries that changed modern healthcare 2026-07-27 · 64m Open
#400 ‒ AMA #87: Environmental pollution and longevity: air pollution, noise, light, EMFs, and practical strategies to mitigate health risks 2026-07-20 · 20m
#399 ‒ The evolution of Alzheimer's disease and dementia care: how early detection, personalized treatment, new therapies, and a multimodal approach are changing the landscape | Gayatri Devi, M.D. 2026-07-13 · 117m
Building strength and muscle mass: how to optimize training, nutrition, and more for longevity (AMA #71 rebroadcast) 2026-07-06 · 104m
#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss 2026-06-29 · 10m
#397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D. 2026-06-22 · 119m
#396 ‒ Breast cancer screening: understanding risk, deciding when to start and how often to screen, and choosing the right imaging strategy 2026-06-15 · 50m
#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D. 2026-06-08 · 101m
#394 ‒ Sleep pharmacology: the role of medications in healthy sleep, the promise of emerging therapies, and the evidence for common sleep supplements 2026-06-01 · 55m
#393 ‒ AMA #85: A guide to medications and supplements: determining what to take, what to skip, and how to know if they're working for you 2026-05-25 · 13m
#392 - Genetic testing: when it's valuable, how to choose the right test, and what to do with the results 2026-05-18 · 62m
#391 ‒ Colorectal cancer screening: importance of early screening, colonoscopy as a screening and preventive tool, and how to build a personalized strategy 2026-05-11 · 8m
#390 ‒ AMA #84: Family health history, preventing heart disease, metabolic health, strength training efficiency, dementia risk reduction, NAD supplements, and hydration 2026-05-04 · 9m
#389 - Thinking scientifically: why it's hard, why it matters, and a practical toolkit 2026-04-27 · 54m
#388 — Prostate cancer screening: why current PSA guidelines are failing men and how modern tools improve early detection and save lives 2026-04-20 · 46m
#387 - AMA #83: Peptides—evaluating the science, safety, and hype in a rapidly growing field 2026-04-13 · 22m
#386 - Aging clocks—what they measure, how they work, and their clinical and real-world relevance 2026-04-06 · 56m
#385 - AMA #82: Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more 2026-03-23 · 19m
#384 - Special episode — Obicetrapib: The CETP inhibitor with cardiovascular benefits and potential Alzheimer's prevention 2026-03-16 · 53m
Alzheimer's disease in women: how hormonal transitions impact the female brain, the role of HRT, genetics, and lifestyle on risk, and emerging diagnostics and therapies | Lisa Mosconi, Ph.D. 2026-01-26 · 127m
The seed oil debate: are they uniquely harmful relative to other dietary fats? | Layne Norton, Ph.D. 2026-01-19 · 128m
AMA #79: A guide to cardiorespiratory training at any fitness level to improve healthspan, lifespan, and long-term independence 2026-01-12 · 39m
Women's health and performance: how training, nutrition, and hormones interact across life stages | Abbie Smith-Ryan, Ph.D. 2026-01-05 · 132m
Building & Changing Habits | James Clear (#183 rebroadcast) 2025-12-29 · 140m
Special episode: Understanding true happiness and the tools to cultivate a meaningful life—insights from past interviews with Arthur Brooks 2025-12-22 · 100m
AMA #78: Longevity interventions, exercise, diagnostic screening, and managing high apoB, hypertension, metabolic health, and more 2025-12-15 · 22m
Ketogenic diet, ketosis & hyperbaric oxygen: metabolic therapies for weight loss, cognition, Alzheimer's & more | Dom D'Agostino, Ph.D. 2025-12-08 · 128m
The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D. 2025-12-01 · 125m
The impact of gratitude, serving others, embracing mortality, and living intentionally | Walter Green (#288 rebroadcast) 2025-11-24 · 91m
Thyroid function and hypothyroidism: why current diagnosis and treatment fall short for many, and how new approaches are transforming care | Antonio Bianco, M.D., Ph.D. 2025-11-17 · 140m
AMA #77: Dietary fiber and health outcomes: real benefits, overhyped claims, and practical applications 2025-11-10 · 24m
Women's sexual health: desire, arousal, and orgasms, navigating perimenopause, and enhancing satisfaction | Sally Greenwald, M.D., M.P.H. 2025-11-03 · 112m
Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more (re-broadcast) 2025-10-27 · 85m
AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — proven, promising, fuzzy, noise, or nonsense? 2025-10-27 · 17m
Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D. 2025-10-20 · 110m
The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D. 2025-10-13 · 109m
Tylenol, pregnancy, and autism: What recent studies show and how to interpret the data 2025-10-06 · 87m
Transforming education with AI and an individualized, mastery-based education model | Joe Liemandt 2025-09-29 · 107m
#365 ‒ Training for longevity: A roundtable on building strength, preventing injury, meeting protein needs, guidance for women and youth athletes, and more | Gabrielle Lyon, Mike Boyle, Jeff Cavaliere 2025-09-22 · 135m
AMA #75: Diets: how to evaluate and implement any diet including keto, carnivore, vegan, Mediterranean, and more 2025-09-15 · 13m
A new frontier in neurosurgery: restoring brain function with brain-computer interfaces, advancing glioblastoma care, and new hope for devastating brain diseases | Edward Chang, M.D. 2025-09-08 · 113m
Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D. (#287 rebroadcast) 2025-09-01 · 151m
Understanding anxiety: defining, assessing, and treating health anxiety, OCD, and the spectrum of anxiety disorders | Josh Spitalnick, Ph.D., A.B.P.P. 2025-08-25 · 135m
AMA #74: Sugar and sugar substitutes: weight control, metabolic effects, and health trade-offs 2025-08-18 · 16m
How to change your habits: why they form and how to build or break them | Charles Duhigg, M.B.A 2025-08-11 · 133m
How metabolic and immune system dysfunction drive the aging process, the role of NAD, promising interventions, aging clocks, and more | Eric Verdin, M.D. 2025-08-04 · 131m
Peter's takeaways on navigating HRT, rejuvenating the face, understanding the biology of aging, optimizing fertility, and learning to live well from the dying | Quarterly Podcast Summary #6 2025-07-28 · 12m
A new era of longevity science: models of aging, human trials of rapamycin, biological clocks, promising compounds, and lifestyle interventions | Brian Kennedy, Ph.D. 2025-07-21 · 117m
AMA #73: Preserving brain health, optimizing exercise programming, improving body composition, and more 2025-07-14 · 17m
Navigating bone health: early life influences and advanced strategies for improvement and injury prevention (#214 rebroadcast) 2025-07-07 · 92m
Skincare strategies, the science of facial aging, and cosmetic-intervention guidance | Tanuj Nakra, M.D. & Suzan Obagi, M.D. 2025-06-30 · 177m
What the dying can teach us about living well: lessons on life and reflections on mortality | BJ Miller, M.D. and Bridget Sumser, L.C.S.W. 2025-06-23 · 136m
AMA #72: Fasting: benefits for body composition and disease prevention, potential risks, and Peter's updated practical framework 2025-06-16 · 20m
Female fertility: optimizing reproductive health, diagnosing and treating infertility and PCOS, and understanding the IVF process | Paula Amato, M.D. 2025-06-09 · 143m
Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D. 2025-06-02 · 139m
Injury prevention, recovery, and performance optimization for every decade | Kyler Brown, D.C. 2025-05-26 · 105m
AMA #71: Building strength and muscle mass: how to optimize training, nutrition, and more for longevity 2025-05-19 · 11m
Women's sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D. 2025-05-12 · 133m
Peter's takeaways on mastering sleep, dealing with chronic pain, developing breakthrough cancer drugs, transforming healthcare with AI, advancing radiation therapy, and healing trauma | Quarterly Podcast Summary #5 2025-05-05 · 33m
Scaling biotech and improving global health: lessons from an extraordinary career in medicine | Susan Desmond-Hellmann, M.D., M.P.H. 2025-04-28 · 126m
Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D. 2025-04-21 · 167m
AMA #70: Nicotine: impact on cognitive function, performance, and mood, health risks, delivery modalities, and smoking cessation strategies 2025-04-14 · 22m
The evolving role of radiation: advancements in cancer treatment, emerging low-dose treatments for arthritis, tendonitis, and injuries, and addressing misconceptions | Sanjay Mehta, M.D. 2025-04-07 · 132m
Aging well: Peter shares strategies for improving longevity with residents at a senior living center 2025-03-31 · 44m
Overcoming insomnia: improving sleep hygiene and treating disordered sleep with cognitive behavioral therapy for insomnia | Ashley Mason, Ph.D. 2025-03-24 · 125m
AMA #69: Scrutinizing supplements: creatine, fish oil, vitamin D, and more—a framework for understanding effectiveness, quality, and individual need 2025-03-17 · 25m
Unpacking trauma: How early wounds shape behavior and the path toward healing | Jeff English 2025-03-10 · 122m
Peter's takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4 2025-03-03 · 28m
Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment | Ralph DeFronzo, M.D. 2025-02-24 · 147m
AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more 2025-02-17 · 27m
The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D. 2025-02-10 · 171m
Cardiovascular disease, the number one killer: development, biomarkers, apoB, cholesterol, brain health, and more | Tom Dayspring, M.D. 2025-02-03 · 138m
Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Matt Kaeberlein, Richard Miller 2025-01-27 · 162m
AMA #67: Microplastics, PFAS, and phthalates: understanding health risks and a framework for minimizing exposure and mitigating risk 2025-01-20 · 25m
Optimizing endurance performance: metrics, nutrition, lactate, and more insights from elite performers | Olav Aleksander Bu (Pt. 2) 2025-01-13 · 136m
Autism, ADHD, and Anxiety: Understanding the rise in autism and a multidisciplinary approach to diagnosis and treatment of each condition in children | Trenna Sutcliffe, M.D. 2025-01-06 · 117m
Building & Changing Habits | James Clear 2024-12-30 · 140m
Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more 2024-12-16 · 27m
AMA #66: Optimizing nutrition for health and longevity: myth of a "best" diet, complexities of nutrition science, and practical steps for building a sustainable diet 2024-12-09 · 17m
Choices, costs, and challenges in US healthcare: insurance intricacies, drug pricing, economic impacts, and potential reforms | Saum Sutaria, M.D. 2024-12-02 · 153m
Optimizing life for maximum fulfillment | Bill Perkins 2024-11-25 · 104m
AMA #65: Red light therapy: promising applications, mixed evidence, and impact on health and aging 2024-11-18 · 15m
Peter's key takeaways on bone health, calorie restriction and energy balance, dopamine and addiction, gene editing, and testosterone therapy safety with a prostate cancer diagnosis | Quarterly Podcast Summary #3 2024-11-11 · 25m
Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D. 2024-11-04 · 129m
CRISPR and the future of gene editing: scientific advances, genetic therapies, disease treatment potential, and ethical considerations | Feng Zhang, Ph.D. 2024-10-28 · 126m
Bone health for life: building strong bones, preventing age-related loss, and reversing osteoporosis with evidence-based exercise | Belinda Beck, Ph.D. 2024-10-21 · 100m
Dopamine and addiction: navigating pleasure, pain, and the path to recovery | Anna Lembke, M.D. 2024-10-14 · 142m
AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) - efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape 2024-10-07 · 21m
Peter's key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2 2024-09-30 · 28m
Cycling phenom and Tour de France champion Tadej Pogačar reveals his training strategies, on-bike nutrition, and future aspirations 2024-09-23 · 46m
Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H. 2024-09-16 · 123m
AMA #63: A guide for hair loss: causes, treatments, transplants, and sex-specific considerations 2024-09-09 · 21m
Improve your decision-making, frameworks for learning, backcasting, and more | Annie Duke 2024-09-02 · 152m
Life after near-death: a new perspective on living, dying, and the afterlife | Sebastian Junger 2024-08-26 · 124m
Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D. 2024-08-19 · 119m
AMA #62: Protein's impact on appetite and weight management, and uric acid's link to disease and how to manage levels 2024-08-12 · 24m
A masterclass in lactate: Its critical role as metabolic fuel, implications for diseases, and therapeutic potential from cancer to brain health and beyond | George A. Brooks, Ph.D. 2024-08-05 · 126m
Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more 2024-07-29 · 85m
The relationship between testosterone and prostate cancer, testosterone replacement therapy, and tools for predicting cancer aggressiveness and guiding therapy | Ted Schaeffer, M.D., Ph.D. 2024-07-22 · 48m
AI in medicine: its potential to revolutionize disease prediction, diagnosis, and outcomes, causes for concern in medicine and beyond, and more | Isaac Kohane, M.D., Ph.D. 2024-07-15 · 115m
Zone 2 training: impact on longevity and mitochondrial function, how to dose frequency and duration, and more | Iñigo San-Millán, Ph.D. 2024-07-08 · 166m
AMA #61: Sun exposure, sunscreen, and skin health: relationship between sun exposure and skin cancer, vitamin D production, and photoaging, how to choose a sunscreen, and more 2024-07-01 · 22m
Exercise for aging people: where to begin, and how to minimize risk while maximizing potential | Peter Attia, M.D. 2024-06-24 · 100m
AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more 2024-06-17 · 18m
Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson 2024-06-10 · 112m
NEW: Introducing quarterly podcast summaries - Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more 2024-06-03 · 31m
A breakthrough in Alzheimer's disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer's disease | Dena Dubal, M.D., Ph.D. 2024-05-27 · 125m
Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage liver disease | Julia Wattacheril, M.D., M.P.H. 2024-05-20 · 145m
AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it 2024-05-13 · 24m
Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise? 2024-05-06 · 100m
Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna's death 2024-04-29 · 149m
Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D. 2024-04-22 · 150m
The impact of emotional health on longevity, self-audit strategies, improving well-being, and more | Paul Conti, M.D. 2024-04-15 · 144m
AMA #58: Iron: its role in health, testing methods, and strategies for preventing and managing iron deficiency 2024-04-08 · 18m
Foot health: preventing and treating common injuries, enhancing strength and mobility, picking footwear, and more | Courtney Conley, D.C. 2024-04-01 · 142m
Roadway death and injury: why everyone should care and what you can do to reduce risk | Mark Rosekind, Ph.D. 2024-03-25 · 149m
Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth | Olav Aleksander Bu 2024-03-18 · 154m
AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity 2024-03-11 · 18m
Rucking: benefits, gear, FAQs, and the journey from Special Forces to founding GORUCK | Jason McCarthy 2024-03-04 · 150m
The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more | Derek, More Plates More Dates Pt.2 2024-02-26 · 158m
The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more | Derek, More Plates More Dates Pt.2 2024-02-26 · 158m
Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging research | Alex Aravanis, M.D., Ph.D. 2024-02-19 · 126m
AMA #56: Cancer screening: pros and cons, screening options, interpreting results, and more 2024-02-12 · 21m
The impact of gratitude, serving others, embracing mortality, and living intentionally | Walter Green 2024-02-05 · 92m
Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D. 2024-01-29 · 156m
Journal club with Andrew Huberman: the impact of light exposure on mental health and an immunotherapy breakthrough for cancer treatment 2024-01-22 · 166m
AMA #55: Exercise: longevity-focused training, goal setting, improving deficiencies, managing emotional stress, and more 2024-01-15 · 22m
Overcoming addictive behaviors, elevating wellbeing, thriving in an era of excess, and the scarcity loop | Michael Easter, M.A. 2024-01-08 · 117m
James Clear: Building & Changing Habits (#183 rebroadcast) 2024-01-01 · 140m
Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D. 2023-12-18 · 153m
AMA #54: Magnesium: risks of deficiency, how to correct it, supplement options, potential cognitive and sleep benefits, and more 2023-12-11 · 21m
Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program (ITP) | Rich Miller, M.D., Ph.D. 2023-12-04 · 144m
Cultivating happiness, emotional self-management, and more | Arthur Brooks Ph.D. 2023-11-27 · 121m
The world's most important doctor to millions in the war-torn and remote villages of Sudan | Tom Catena, M.D. 2023-11-20 · 160m
AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins 2023-11-13 · 27m
Breast cancer: how to catch, treat, and survive breast cancer | Harold Burstein, M.D., Ph.D. 2023-11-06 · 130m
Food allergies: causes, prevention, and treatment with immunotherapy | Kari Nadeau, M.D., Ph.D. 2023-10-30 · 106m
Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more 2023-10-23 · 79m
AMA #52: Hormone replacement therapy in women: practical applications and the role of compounding pharmacies 2023-10-16 · 18m
Performance-enhancing drugs and hormones: risks, rewards, and broader implications for the public | Derek: More Plates, More Dates 2023-10-09 · 195m
Prostate health: common problems, cancer prevention, screening, treatment, and more | Ted Schaeffer, M.D., Ph.D. 2023-10-02 · 209m
Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more | David Sabatini, M.D., Ph.D. and Matt Kaeberlein, Ph.D. 2023-09-25 · 171m
AMA #51: Understanding and improving your metabolic health 2023-09-18 · 20m
Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers 2023-09-11 · 137m
Good vs. bad science: how to read and understand scientific studies 2023-09-04 · 111m
Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D. 2023-08-28 · 147m
The latest in cancer therapeutics, diagnostics, and early detection | Keith Flaherty, M.D. 2023-08-21 · 110m
AMA #50: Genetics: how they impact disease risk, what you can do about it, testing, and more 2023-08-14 · 27m
Time, productivity, and purpose: insights from Four Thousand Weeks | Oliver Burkeman 2023-08-07 · 110m
Hip, knee, ankle, and foot: common injuries, prevention, and treatment options 2023-07-31 · 130m
Concussions and head trauma: symptoms, treatment, and recovery | Micky Collins, Ph.D. 2023-07-24 · 81m
AMA #49: Heart rate recovery, strength training, rucking, kidney function, and brain health 2023-07-17 · 20m
Training for The Centenarian Decathlon: zone 2, VO2 max, stability, and strength | Peter Attia, M.D. 2023-07-10 · 65m
Training for The Centenarian Decathlon: zone 2, VO2 max, stability, and strength | Peter Attia, M.D. 2023-07-10 · 65m
Cancer screening with full-body MRI scans and a seminar on the field of radiology | Rajpaul Attariwala, M.D., Ph.D. (#61 rebroadcast) 2023-07-03 · 130m
Men's Sexual Health: why it matters, what can go wrong, and how to fix it | Mohit Khera, M.D., M.B.A., M.P.H. 2023-06-26 · 153m
Women's sexual health: Why it matters, what can go wrong, and how to fix it | Sharon Parish, M.D. 2023-06-19 · 169m
AMA #48: Blood pressure—how to measure, manage, and treat high blood pressure 2023-06-12 · 26m
Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies, supplements, and more | Tommy Wood, M.D., Ph.D. 2023-06-05 · 127m
The endocrine system: exploring thyroid, adrenal, and sex hormones | Peter Attia, M.D. 2023-05-29 · 57m
Latest therapeutics in CVD, APOE's role in Alzheimer's disease and CVD, familial hypercholesterolemia, and more | John Kastelein, M.D., Ph.D. 2023-05-22 · 124m
AMA #47: Cold therapy: pros, cons, and its impact on longevity 2023-05-15 · 14m
Hormone replacement therapy and the Women's Health Initiative: re-examining the results, the link to breast cancer, and weighing the risk vs reward of HRT | JoAnn Manson, M.D. 2023-05-08 · 81m
Latest insights on Alzheimer's disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D. 2023-05-01 · 150m
The impact of stress on our physical and emotional health | Robert Sapolsky, Ph.D. (#51 rebroadcast) 2023-04-24 · 136m
AMA #46: Optimizing brain health: Alzheimer's disease risk factors, APOE, prevention strategies, and more 2023-04-17 · 34m
Training principles for longevity | Andy Galpin, Ph.D. (PART II) 2023-04-10 · 167m
How the brain works, Andrew's fascinating backstory, improving scientific literacy, and more | Andrew Huberman, Ph.D. 2023-04-03 · 171m
OUTLIVE book: A behind-the-scenes look into the writing of this book, motivation, main themes, and more 2023-03-28 · 102m
Preventing cardiovascular disease: the latest in diagnostic imaging, blood pressure, metabolic health, and more | Ethan Weiss, M.D. 2023-03-20 · 133m
AMA #45: Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent 2023-03-13 · 28m
Overcoming trauma, finding inner peace, and living a meaningful and fulfilling life | Lewis Howes 2023-03-06 · 94m
The history of the cell, cell therapy, gene therapy, and more | Siddhartha Mukherjee 2023-02-27 · 101m
The fentanyl crisis and why everyone should be paying attention | Anthony Hipolito 2023-02-20 · 67m
AMA #44: Peter's historical changes in body composition with his evolving dietary, fasting, and training protocols 2023-02-13 · 25m
#241 ‒ Living intentionally, valuing time, prioritizing relationships, and more keys to a rich life | Ric Elias (Part 2) 2023-02-06 · 83m
The confusion around HDL and its link to cardiovascular disease | Dan Rader, M.D. 2023-01-30 · 114m
The science of strength, muscle, and training for longevity | Andy Galpin, Ph.D. (PART I) 2023-01-23 · 155m
AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease 2023-01-16 · 24m
Optimizing life for maximum fulfillment | Bill Perkins 2023-01-09 · 104m
Neurodegenerative disease: pathology, screening, and prevention | Kellyann Niotis, M.D. 2023-01-02 · 117m
James Clear: Building & Changing Habits (#183 rebroadcast) 2022-12-26 · 139m
Training principles for mass and strength, changing views on nutrition, creatine supplementation, and more | Layne Norton, Ph.D. 2022-12-19 · 168m
Chris Hemsworth on Limitless, longevity, and happiness 2022-12-12 · 71m
AMA #42: Optimizing sleep - bedtime routine, molecule regimen, sleep trackers, sauna, & more 2022-12-05 · 24m
Shoulder, elbow, wrist, and hand: diagnosis, treatment, and surgery of the upper extremities | Alton Barron, M.D. 2022-11-28 · 218m
A masterclass on insulin resistance—mechanisms and implications | Gerald Shulman, M.D., Ph.D. (#140 rebroadcast) 2022-11-21 · 127m
AMA #41: Medicine 3.0, developments in the field of aging, healthy habits in times of stress, and more 2022-11-14 · 16m
Cardiovascular disease in women: prevention, risk factors, lipids, and more | Erin Michos, M.D. 2022-11-07 · 135m
Understanding cardiovascular disease risk, cholesterol, and apoB 2022-10-31 · 79m
Improving body composition, female-specific training principles, and overcoming an eating disorder | Holly Baxter, APD 2022-10-24 · 135m
AMA #40: Body composition, protein, time-restricted feeding, fasting, DEXA scans, and more 2022-10-17 · 16m
The science of happiness | Arthur Brooks, Ph.D. 2022-10-10 · 100m
The comfort crisis, doing hard things, rucking, and more | Michael Easter, MA 2022-10-03 · 109m
Dietary protein: amount needed, ideal timing, quality, and more | Don Layman, Ph.D. 2022-09-26 · 123m
AMA #39: The Centenarian Decathlon, zone 2, VO2 max, and more 2022-09-19 · 17m
How nutrition impacts longevity | Matt Kaeberlein, Ph.D 2022-09-12 · 147m
Understanding sleep and how to improve it 2022-09-05 · 97m
Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D. 2022-08-29 · 88m
Dialectical behavior therapy (DBT): skills for overcoming depression , emotional dysregulation, and more | Shireen Rizvi, Ph.D., ABPP 2022-08-22 · 136m
AMA #38: Can you exercise too much? 2022-08-15 · 17m
Exercise, VO2 max, and longevity | Mike Joyner, M.D. 2022-08-08 · 113m
Metabolomics, NAD+, and cancer metabolism | Josh Rabinowitz, M.D., Ph.D. 2022-08-01 · 132m
The gut-brain connection | Michael Gershon, M.D. 2022-07-25 · 133m
AMA #37: Bone health—everything you need to know 2022-07-18 · 17m
Liquid biopsies and cancer detection | Max Diehn, M.D. Ph.D. 2022-07-11 · 127m
Earning the gift of life | Ric Elias (#79 rebroadcast) 2022-07-04 · 100m
The neuroscience of obesity | Stephan Guyenet, Ph.D. 2022-06-27 · 145m
AMA #36: Fruits & vegetables—everything you need to know 2022-06-20 · 20m
Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D. 2022-06-13 · 127m
Medical mistakes, patient safety, and the RaDonda Vaught case | Marty Makary, M.D., M.P.H. 2022-06-06 · 105m
The Art of Stability | Beth Lewis (Ep. #131 Rebroadcast) 2022-05-30 · 109m
Tragedy, grief, healing, and finding happiness | Kelsey Chittick 2022-05-23 · 115m
AMA #35: "Anti-Aging" Drugs — NAD+, metformin, & rapamycin 2022-05-16 · 31m
Exercising for longevity: strength, stability, zone 2, zone 5, and more 2022-05-09 · 74m
Energy balance, nutrition, & building muscle | Layne Norton, Ph.D. (Pt.2) 2022-05-02 · 176m
Centenarians, metformin, and longevity | Nir Barzilai, M.D. 2022-04-25 · 150m
AMA #34: What Causes Heart Disease? 2022-04-18 · 17m
Peter on nutrition, disease prevention, sleep, and more — looking back on the last 100 episodes 2022-04-11 · 117m
In remembrance of Sarah Hallberg, D.O., M.S. (Ep. #162 Rebroadcast) 2022-04-04 · 137m
Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2) 2022-03-28 · 166m
AMA #33: Hydration—electrolytes, supplements, sports drinks, performance effects, and more 2022-03-21 · 19m
Running, overcoming challenges, and finding success | Ryan Hall 2022-03-14 · 176m
Eye health—everything you need to know | Steven Dell, M.D. 2022-03-07 · 164m
The science of obesity & how to improve nutritional epidemiology | David Allison, Ph.D. 2022-02-28 · 134m
AMA #32: Exercise, squats, deadlifts, BFR, and TRT 2022-02-21 · 19m
Freedom, PTSD, war, and life through an evolutionary lens | Sebastian Junger 2022-02-14 · 177m
How fructose drives metabolic disease | Rick Johnson, M.D. 2022-02-07 · 125m
AMA #31: Heart rate variability (HRV), alcohol, sleep, and more 2022-01-31 · 14m
COVID Part 2: Masks, long COVID, boosters, mandates, treatments, and more 2022-01-24 · 173m
Revolutionizing our understanding of mental illness with optogenetics | Karl Deisseroth M.D., Ph.D. 2022-01-17 · 149m
Paul Conti, M.D.: How to heal from trauma and break the cycle of shame 2022-01-10 · 141m
COVID-19: Current state of affairs, Omicron, and a search for the end game 2022-01-03 · 165m
Iñigo San Millán, Ph.D.: Zone 2 Training and Metabolic Health (Ep. #85 Rebroadcast) 2021-12-27 · 171m
AMA #30: How to Read and Understand Scientific Studies 2021-12-20 · 30m
Sam Apple: The Warburg Effect—Otto Warburg's cancer metabolism theory 2021-12-13 · 108m
Patrick Radden Keefe: The opioid crisis—origin, guilty parties, and the difficult path forward 2021-12-06 · 116m
Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way we assess risk 2021-11-29 · 122m
Rick Johnson, M.D.: Metabolic Effects of Fructose (Ep. #87 Rebroadcast) 2021-11-22 · 110m
AMA #29: GLP-1 Agonists—The Future of Treating Obesity? 2021-11-15 · 14m
James Clear: Building & changing habits 2021-11-08 · 139m
David Nutt: Psychedelics & Recreational Drugs 2021-11-01 · 99m
Robert Gatenby, M.D.: Viewing cancer through an evolutionary lens and why this offers a radically different approach to treatment 2021-10-25 · 120m
AMA #28: All things testosterone and testosterone replacement therapy 2021-10-18 · 21m
Jeremy Loenneke, Ph.D.: The science of blood flow restriction—benefits, uses, and what it teaches us about the relationship between muscle size and strength 2021-10-11 · 119m
Lance Armstrong: The rise, fall, and growth of a cycling legend 2021-10-04 · 118m
Steven Rosenberg, M.D., Ph.D.: The development of cancer immunotherapy and its promise for treating advanced cancers 2021-09-27 · 126m
AMA #27: The importance of muscle mass, strength, and cardiorespiratory fitness for longevity 2021-09-20 · 19m
Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process 2021-09-13 · 161m
Lawrence Wright: The 20th anniversary of the 9/11 attacks: reflections on how they happened, and lessons learned and not learned 2021-09-06 · 182m
AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions 2021-08-23 · 20m
Esther Perel: The effects of trauma, the role of narratives in shaping our worldview, and why we need to accept uncomfortable emotions 2021-08-16 · 124m
Steve Austad, Ph.D.: The landscape of longevity science: making sense of caloric restriction, biomarkers of aging, and possible geroprotective molecules 2021-08-09 · 147m
AMA #25: Navigating the complexities and nuances of cancer screening 2021-07-26 · 12m
Katherine Eban: COVID-19 Lab Leak: Examining all sides of the debate and discussing barriers to a full investigation 2021-07-19 · 100m
Hugh Jackman: Reflections on acting, identity, personal transformation, and the significance of being Wolverine 2021-07-12 · 130m
Gary Taubes: Bad science and challenging the conventional wisdom of obesity 2021-06-28 · 157m
Patricia Corby, D.D.S.: Importance of oral health, best hygiene practices, and the relationship between poor oral health and systemic disease 2021-06-21 · 121m
AMA #24: Deep dive into blood glucose: why it matters, important metrics to track, and superior insights from a CGM 2021-06-14 · 17m
Amanda Smith, M.D.: Diagnosing, preventing, and treating Alzheimer's disease, and what we can all learn from patients with dementia 2021-06-07 · 122m
Layne Norton, Ph.D.: Building muscle, losing fat, and the importance of resistance training 2021-05-24 · 161m
Sarah Hallberg, D.O., M.S.: Challenging the status quo of treating metabolic disease, and a personal journey through a grim cancer diagnosis 2021-05-17 · 141m
AMA #23: All Things Nicotine: deep dive into its cognitive and physical benefits, risks, and mechanisms of action 2021-05-10 · 20m
Paul Offit, M.D.: The latest on COVID-19 vaccines and their safety, herd immunity, and viral variants 2021-05-03 · 86m
Peter Hotez, M.D., Ph.D.: Evolution of the anti-vaccine movement, the causes of autism, and COVID-19 vaccine state of affairs 2021-04-26 · 115m
Brian Deer: A tale of scientific fraud—exposing Andrew Wakefield and the origin of the belief that vaccines cause autism 2021-04-19 · 110m
AMA #22: Losing fat and gaining fat: the lessons of fat flux 2021-04-12 · 15m
Jake Muise: Humanely harvesting axis deer while alleviating its impact on Hawaii's vulnerable ecosystems 2021-04-05 · 140m
Chris Sonnenday, M.D.: The history, challenges, and gift of organ transplantation 2021-03-29 · 135m
Steve Levitt, Ph.D.: A rogue economist's view on climate change, mental health, the ethics of experiments, and more 2021-03-22 · 120m
AMA #21: Deep dive into olive oil, high-intensity exercise, book update, and more 2021-03-15 · 14m
Michael Rintala, D.C.: Principles of Dynamic Neuromuscular Stabilization (DNS) 2021-03-08 · 96m
Alex Hutchinson, Ph.D.: Translating the science of endurance and extreme human performance 2021-03-01 · 134m
Senator Bill Frist, M.D.: A modern Renaissance man's journey through science, politics, and business 2021-02-22 · 144m
AMA #20: Simplifying the complexities of insulin resistance: how it's measured, how it manifests in the muscle and liver, and what we can do about it 2021-02-15 · 23m
Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the Interventions Testing Program 2021-02-08 · 134m
Hussein Yassine, M.D.: Deep dive into the "Alzheimer's gene" (APOE), brain health, and omega-3s 2021-02-01 · 126m
Guy Winch, Ph.D.: Emotional first aid and how to treat psychological injuries 2021-01-25 · 117m
AMA #19: Deep dive on Zone 2 training, magnesium supplementation, and how to engage with your doctor 2021-01-18 · 18m
Phil Maffetone: Optimizing health and performance through maximal aerobic function 2021-01-11 · 82m
John Ioannidis, M.D., D.Sc.: Why most biomedical research is flawed, and how to improve it 2021-01-04 · 112m
Robert Abbott: The Bobby Knight story—a cautionary tale of unchecked anger, ego, and winning at all costs 2020-12-21 · 134m
AMA #18: Deep dive: sugar and sugar substitutes 2020-12-14 · 16m
Gerald Shulman, M.D., Ph.D.: A masterclass on insulin resistance—molecular mechanisms and clinical implications 2020-12-07 · 129m
Kristin Neff, Ph.D.: The power of self-compassion 2020-11-30 · 77m
Lauren Miller Rogen and Richard Isaacson, M.D.: Alzheimer's disease prevention—patient and doctor perspectives 2020-11-23 · 132m
Paul Offit, M.D.: An expert perspective on COVID-19 vaccines 2020-11-16 · 96m
AMA #17: Body composition methods tour de force, insulin resistance, and Topo Chico 2020-11-09 · 18m
BJ Miller, M.D.: How understanding death leads to a better life 2020-11-02 · 115m
James O'Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise. 2020-10-26 · 129m
Vinay Prasad, M.D., M.P.H: Hallmarks of successful cancer policy 2020-10-19 · 132m
AMA #16: Exploring hot and cold therapy 2020-10-12 · 19m
Beth Lewis: The Art of Stability: Learning about pain, mitigating injury, and moving better through life 2020-10-05 · 111m
Carol Tavris, Ph.D. & Elliot Aronson, Ph.D.: Recognizing and overcoming cognitive dissonance 2020-09-28 · 120m
Tom Dayspring, M.D.: The latest insights into cardiovascular disease and lipidology 2020-09-21 · 120m
Irene Davis, Ph.D.: The evolution of the foot, running injuries, and minimalist shoes 2020-09-14 · 113m
AMA #3 with sleep expert, Matthew Walker, Ph.D.: Fasting, gut health, blue light, caffeine, REM sleep, and more 2020-09-07 · 16m
Matthew Walker, Ph.D.: Sleep and immune function, chronotypes, hygiene tips, and addressing questions about his book 2020-08-31 · 102m
John Arnold: The most prolific philanthropist you may not have heard of 2020-08-24 · 148m
AMA #15: Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more 2020-08-17 · 17m
Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and metformin—longevity, immune enhancement, and COVID-19 2020-08-10 · 138m
Lori Gottlieb: Understanding pain, therapeutic breakthroughs, and keys to enduring emotional health 2020-08-03 · 90m
Azra Raza, M.D.: Why we're losing the war on cancer 2020-07-27 · 115m
AMA with Dom D'Agostino, Ph.D., Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health 2020-07-20 · 28m
Terry Real: Breaking the cycle of shame, anger, and depression 2020-07-13 · 100m
Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging 2020-07-06 · 135m
Stanley Perlman, M.D., Ph.D.: Insights from a coronavirus expert on COVID-19 2020-06-29 · 104m
AMA with Dom D'Agostino, Ph.D., Part I of II: Ketogenic diet, exogenous ketones, and exercise 2020-06-22 · 28m
David Watkins, Ph.D.: A masterclass in immunology, monoclonal antibodies, and vaccine strategies for COVID-19 2020-06-15 · 98m
Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies 2020-06-08 · 119m
Normative errors—a conversation with my daughter about current events 2020-06-03 · 22m
Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it 2020-06-01 · 136m
AMA #14: What lab tests can (and cannot) inform us about our overall objective of longevity 2020-05-18 · 17m
Lew Cantley, Ph.D.: Cancer metabolism, cancer therapies, and the discovery of PI3K 2020-05-11 · 131m
John Dudley: The beauty in archery, the love of practice, and a model system for life 2020-05-04 · 137m
AMA #13: 3-day fasting, exogenous ketones, autophagy, and exercise for longevity 2020-04-21 · 16m
John Barry: 1918 Spanish flu pandemic—historical account, parallels to today, and lessons 2020-04-17 · 82m
Amesh Adalja, M.D.: Comparing COVID-19 to past pandemics, preparing for the future, and reasons for optimism 2020-04-13 · 44m
Paul Conti, M.D.: The psychological toll of a pandemic, and the societal problems it has highlighted 2020-04-10 · 87m
COVID-19 for kids with Olivia Attia 2020-04-08 · 34m
Looking back on the first 99 episodes: Strong Convictions, Loosely Held 2020-04-06 · 77m
Michael Osterholm, Ph.D.: COVID-19—Lessons learned, challenges ahead, and reasons for optimism and concern 2020-03-31 · 82m
Ryan Holiday: Finding stillness amidst chaos 2020-03-27 · 83m
Sam Harris, Ph.D.: COVID-19—Comprehending the crisis and managing our emotions 2020-03-24 · 92m
Peter Hotez, M.D., Ph.D.: Continuing the conversation on COVID-19 2020-03-20 · 66m
Qualy #129 - Evolutionary reasons to sleep 2020-03-17 · 10m
Peter Attia, M.D. and Paul Grewal, M.D.: Coronavirus (COVID-19) FAQ 2020-03-15 · 65m
Peter Hotez, M.D., Ph.D.: COVID-19: transmissibility, vaccines, risk reduction, and treatment 2020-03-14 · 57m
Qualy #125 - Hierarchies in healthcare, physician burnout, and a broken system 2020-03-10 · 13m
David Epstein: How a range of experience leads to better performance in a highly specialized world 2020-03-09 · 157m
Qualy #121 - The "art" of longevity: the challenge of preventative medicine and understanding risk 2020-03-03 · 10m
Luke Bennett, M.D.: The emotional, cognitive, and physical demands that make Formula 1 a unique and special sport 2020-03-02 · 99m
Qualy #120 - What is the difference between ketone salts and esters? 2020-02-28 · 6m
Mark Hyman, M.D.: The impact of the food system on our health and the environment 2020-02-24 · 110m
Qualy #116 - Dealing with anger in spots where you know it's coming 2020-02-21 · 9m
AMA with Jason Fried: Work-life balance, avoiding burnout, defining success, company culture, and more 2020-02-17 · 128m
Qualy #109 - How does one select the right physician as a patient? 2020-02-11 · 10m
AMA #12: Strategies for longevity (which don't require a doctor) 2020-02-10 · 15m
Qualy #106 - Does LDL cause heart disease? 2020-02-05 · 10m
Eric Topol, M.D.: Can AI empower physicians and revolutionize patient care? 2020-02-03 · 121m
Qualy #102 - Is the food industry still saying that all calories contribute equally to adiposity and insulin resistance? 2020-01-29 · 8m
Ryan Holiday: Stillness, stoicism, and suffering less 2020-01-27 · 136m
Qualy #99 - The steroid controversy: Mark's use of them and Peter's perspective 2020-01-23 · 11m
AMA #11: All things fasting 2020-01-20 · 15m
Qualy #94 - Comparing the two broad types of meditation, and Peter's favorite meditation apps 2020-01-15 · 7m
Paul Grewal, M.D.: Treating metabolic disease and strategies for long-term health 2020-01-13 · 139m
Qualy #89 - Cortisol and healthy aging 2020-01-07 · 10m
Rick Johnson, M.D.: Fructose—The common link in high blood pressure, insulin resistance, T2D, & obesity? 2020-01-06 · 111m
Qualy #85 - The past, present, and future of medicine, hospitals, and healthcare 2019-12-31 · 13m
Damon Hill: Overcoming loss, achieving success, and finding one's identity 2019-12-30 · 147m
Qualy #82 - What is the most common first presentation of heart disease? 2019-12-25 · 7m
Iñigo San Millán, Ph.D.: Mitochondria, exercise, and metabolic health 2019-12-23 · 173m
Qualy #80 - The four pillars of charity: water that helped it overcome the stigma of nonprofits and become successful 2019-12-20 · 12m
AMA #10: Low testosterone, hypothyroidism, building muscle (and preserving it while fasting) 2019-12-16 · 11m
Qualy #73 - How can we change the food system when 10 companies control almost 90 percent of the calories we consume in the US? 2019-12-10 · 9m
Bill Harris, Ph.D.: Omega-3 fatty acids 2019-12-09 · 122m
Qualy #69 - Advice to parents and kids for creating a sustainable environment that's going to prevent them from running into metabolic problems 2019-12-03 · 9m
Mark Messier: Leadership, personal growth, and performing under pressure 2019-12-02 · 130m
Qualy #65 - The three laws of medicine — Law #1: A strong intuition is much more powerful than a weak test 2019-11-26 · 6m
Debra Kimless, M.D. & Steve Goldner, J.D.: Cannabis – the latest science on CBD & THC 2019-11-25 · 132m
Qualy #61 - Rapamycin in cancer treatment 2019-11-19 · 10m
Celebrity AMA #1: Fasting, rapamycin, performance vs. longevity, and more 2019-11-18 · 12m
Qualy #57 - A primer on NAD+/NADH, its effect on lifespan/healthspan, and a review of the supplements 2019-11-12 · 8m
Ric Elias: Earning the gift of life 2019-11-11 · 102m
Qualy #53 - Screening for prostate cancer 2019-11-05 · 17m
Sasha Cohen: The price of achievement, and redefining success 2019-11-04 · 134m
Qualy #52 - Insights about berberine 2019-11-01 · 5m
AMA #2 with sleep expert, Matthew Walker, Ph.D.: short sleep mutants, optimal sleep environment, sleep apnea, & rapid fire questions 2019-10-28 · 29m
Qualy #46 - Rapamycin's effects on cancer, cardiovascular disease, and neurodegeneration 2019-10-23 · 8m
Kyle Kingsbury: Finding meaning, depression, and psychedelics 2019-10-21 · 102m
Qualy #43 - What are Peter's thoughts on fasting and ketosis for females? 2019-10-17 · 8m
David Light: Zantac recall due to cancer concerns – what you need to know 2019-10-14 · 98m
Qualy #38 - Finding meaning in struggle and why we are less happy than ever (David Foster Wallace) 2019-10-09 · 7m
Jason Fried: Optimizing efficiency and work-life balance 2019-10-07 · 145m
Qualy #33 - How silent bravado and incessant striving can lead to a functional (and actual) death, and why Paul is critical of the current state of psychiatry 2019-10-01 · 9m
AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more 2019-09-30 · 16m
Qualy #29 - Fasting as a powerful drug in the toolbox of medicine (sneak peek of Paul Grewal's upcoming episode) 2019-09-24 · 6m
Dan Harris: 10% happier – meditation, kindness, and compassion 2019-09-23 · 145m
Qualy #26 - What is Peter looking to achieve and monitor with his blood glucose monitor? 2019-09-18 · 13m
Katherine Eban: Widespread fraud in the generic drug industry 2019-09-16 · 162m
Qualy #24 - What are the "ABCs" of Alzheimer's prevention? 2019-09-13 · 11m
David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD) 2019-09-09 · 130m
Qualy #19 - A unifying theory of aging 2019-09-05 · 11m
Ronesh Sinha, M.D.: Insights into the manifestation of metabolic disease in a patient population predisposed to metabolic syndrome, and what it teaches us more broadly 2019-09-02 · 119m
Qualy #16 - How much does cognitive activity ward off cognitive decline? 2019-08-30 · 7m
Marty Makary, M.D.: The US healthcare system—why it's broken, steps to fix it, and how to protect yourself 2019-08-26 · 170m
Qualy #9 - The importance of exercise for brain health 2019-08-20 · 9m
AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more 2019-08-19 · 18m
Qualy #6 - What are the best lab tests to request specifically for longevity 2019-08-14 · 10m
Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer's disease, and Parkinson's disease – do all roads lead to mitochondria? 2019-08-12 · 148m
Qualy #1 - What are Peter's thoughts on alcohol consumption and health? 2019-08-06 · 12m
Rick Doblin, Ph.D.: MDMA— the creation, scheduling, toxicity, therapeutic use, and changing public opinion of what is possibly the single most important synthetic molecule ever created by our species 2019-08-05 · 181m
Zol Kryger, M.D.: Navigating the sometimes shady world of plastic surgery—understanding potential complications of common procedures and how to reduce your risk by choosing the right doctor and asking the right questions 2019-07-29 · 133m
AMA #7: Exercise framework, deadlifting, lower back pain, blood pressure, nootropics, CGM, and more 2019-07-22 · 13m
Keith Flaherty, M.D.: Deep dive into cancer—History of oncology, novel approaches to treatment, and the exciting and hopeful future 2019-07-15 · 177m
Rajpaul Attariwala, M.D., Ph.D.: Cancer screening with full-body MRI scans and a seminar on the field of radiology 2019-07-08 · 133m
The one-year anniversary episode with Olivia Attia: Reflecting on the past year and looking forward to exciting times ahead 2019-07-02 · 17m
Annie Duke, decision strategist: Poker as a model system for life—how to improve decision making, use frameworks for learning, and apply 'backcasting' to boost your odds for future success 2019-07-01 · 156m
Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness 2019-06-24 · 162m
AMA with sleep expert, Matthew Walker, Ph.D.: Strategies for sleeping more, sleeping better, and avoiding things that are disrupting sleep 2019-06-17 · 29m
Rick Rubin, legendary music producer: collaborating with sensitive psyche of greatest living musicians, and his personal story of weight loss and spiritual quest 2019-06-10 · 184m
Jocko Willink, retired Navy SEAL, Part II of II: Sleep, fasting, raising kids, discipline, taking ownership, and the impact of war 2019-06-03 · 92m
Jocko Willink, retired Navy SEAL, Part I of II: objective, strategy & tactics, leadership, protocols, dealing with death, and applying the many lessons learned from war 2019-05-27 · 159m
Kevin Sayer, CEO of Dexcom: Continuous glucose monitors – impact of food, sleep, and stress on glucose, the unmatched power of CGM to drive behavioral change, and the exciting future of CGM 2019-05-20 · 105m
AMA #6: Fasting framework, vitamin supplementation, antioxidants, time management, problem-solving, and more 2019-05-13 · 12m
Ethan Weiss, M.D.: A masterclass in cardiovascular disease and growth hormone - two topics that are surprising interrelated 2019-05-06 · 174m
The Ayrton Senna Episode (re-release): Celebrating the greatest driver in Formula 1 history and the cautionary tales of driven individuals 2019-05-01 · 63m
Robert Sapolsky, Ph.D.: The pervasive effect of stress - is it killing you? 2019-04-29 · 139m
AMA #5: calcium scores, centenarian olympics, exercise, muscle glycogen, keto, and more 2019-04-22 · 12m
Matthew Walker, Ph.D., on sleep – Part III of III: The penetrating effects of poor sleep from metabolism to performance to genetics, and the impact of caffeine, alcohol, THC, and CBD on sleep 2019-04-15 · 121m
Matthew Walker, Ph.D., on sleep – Part II of III: Heart disease, cancer, sexual function, and the causes of sleep disruption (and tips to correct it) 2019-04-08 · 125m
Matthew Walker, Ph.D., on sleep – Part I of III: Dangers of poor sleep, Alzheimer's risk, mental health, memory consolidation, and more. 2019-04-01 · 103m
Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more 2019-03-25 · 172m
AMA #4: sleep, jet lag protocol, autophagy, metformin, and more 2019-03-18 · 12m
Jeremy Schaap, ESPN journalist: upsets, doping, triumphs, and the importance of sports 2019-03-11 · 102m
Alan Bauman, M.D.: The science of male and female hair restoration - how to protect, enhance, and restore the appearance and health of the hair and scalp 2019-03-04 · 116m
Avrum Bluming, M.D., and Carol Tavris, Ph.D.: Controversial topic affecting all women—the role of hormone replacement therapy through menopause and beyond—the compelling case for long-term HRT and dispelling the myth that it causes breast cancer 2019-02-25 · 141m
Jake Kushner, M.D.: How to thrive with type 1 diabetes and how everyone can benefit from the valuable insights 2019-02-18 · 128m
Tom Catena, M.D.: The world's most important doctor – to nearly a million patients – saving countless lives in the war-torn and remote villages of Sudan 2019-02-11 · 162m
Ted Schaeffer, M.D., Ph.D.: How to catch, treat, and survive prostate cancer 2019-02-04 · 152m
Francisco Gonzalez-Lima, Ph.D.: Advancing Alzheimer's disease treatment and prevention – is AD actually a vascular and metabolic disease? 2019-01-28 · 152m
Zubin Damania, M.D.: Revolutionizing healthcare one hilariously inspiring video at a time 2019-01-21 · 171m
Eric Chehab, M.D.: Extending healthspan and preserving quality of life 2019-01-14 · 159m
Nir Barzilai, M.D.: How to tame aging 2019-01-07 · 168m
Sam Harris, Ph.D.: The transformative power of mindfulness 2018-12-20 · 164m
Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin 2018-12-17 · 140m
Siddhartha Mukherjee, M.D., Ph.D.: new frontiers in cancer therapy, medicine, and the writing process 2018-12-10 · 65m
Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease 2018-12-03 · 142m
Thomas Seyfried, Ph.D.: Controversial discussion—cancer as a mitochondrial metabolic disease? 2018-11-26 · 168m
Apolo Anton Ohno: 8-time Olympic medalist – extreme training, discipline, pursuing perfection, and responding to adversity 2018-11-19 · 218m
Mark and Chris Bell: steroids, powerlifting, addiction, diet, training, helping others, documentaries, and living your best life 2018-11-12 · 131m
David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging 2018-11-05 · 101m
AMA #3: supplements, women's health, patient care, and more 2018-10-29 · 129m
Scott Harrison: transformation, finding meaning, and taking on the global water crisis 2018-10-22 · 139m
Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more 2018-10-19 · 90m
Tom Dayspring, M.D., FACP, FNLA – Part IV of V: Statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brain 2018-10-18 · 120m
Tom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteins 2018-10-17 · 64m
Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation 2018-10-16 · 87m
Thomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology 2018-10-15 · 74m
Dave Feldman: stress testing the lipid energy model 2018-10-08 · 190m
Richard Isaacson, M.D.: Alzheimer's prevention 2018-10-01 · 144m
Mike Trevino: life-lessons from ultra-endurance, mindset, hard work, and removing limitations 2018-09-24 · 116m
Formula 1 (with Paul Conti): the best drivers, Ayrton Senna, and the cautionary tales of driven individuals 2018-09-20 · 63m
Paul Conti, M.D.: trauma, suicide, community, and self-compassion 2018-09-17 · 129m
Robert Lustig, M.D., M.S.L.: fructose, processed food, NAFLD, and changing the food system 2018-09-10 · 83m
Brett Kotlus, M.D.: How to look younger while you live longer 2018-09-03 · 109m
Corey McCarthy: Overcoming trauma, dealing with shame, finding meaning, changing the self-narrative, redemption, and the importance of gratitude 2018-08-27 · 147m
AMA #2: the Nothingburger — results from Peter's week-long fast between two weeks of nutritional ketosis — and answering questions on all things fasting 2018-08-23 · 111m
Matt Kaeberlein, Ph.D.: rapamycin and dogs — man's best friends? — living longer, healthier lives and turning back the clock on aging, and age-related diseases 2018-08-20 · 93m
David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity? 2018-08-13 · 71m
Tom Bilyeu: nutrition, fasting, meditation, mindset, immortality, and the secret formula of fulfillment 2018-08-06 · 98m
Deep Dive: Lp(a) — what every doctor, and the 10-20% of the population at risk, needs to know 2018-07-30 · 76m
D.A. Wallach: music, medicine, cancer screening, and disruptive technologies 2018-07-23 · 140m
Dom D'Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer 2018-07-16 · 163m
AMA #1: alcohol, best lab tests, wearables, finding the right doc, racing, and more 2018-07-09 · 134m
Ron Krauss, M.D.: a deep dive into heart disease 2018-07-02 · 116m
Rhonda Patrick, Ph.D.: the performance and longevity paradox of IGF-1, ketogenic diets and genetics, the health benefits of sauna, NAD+, and more 2018-07-02 · 110m
Tim Ferriss: depression, psychedelics, and emotional resilience 2018-07-02 · 156m
Sneak Peek: The Peter Attia Drive 2018-06-19 · 6m
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